retrospective study of ovarian tumours and tumour-like lesions

Ovaries are common site of non-neoplastic and neoplastic lesions. They can present from the neonatal period to post menopause. Most are functional in nature and resolve with minimal treatment. Objective of the study was to determine the nature of various ovarian lesions and to ascertain the frequency and distribution of the various non-neoplastic and neoplastic lesions. The study was a retrospective review of all cases of ovarian cancer, benign ovarian neoplasm and functional ovarian cysts received during Jan-Dec 2008 at Chughtai's Lahore Laboratory. The clinical data of the patients was obtained from their respective files. A total of 498 different non-neoplastic and neoplastic lesions were seen during one calendar year 2008. Non-neoplastic cysts were more common [343, 68.87%] than neoplastic tumours [155, 31.12%]. The commonest non-neoplastic cyst was luteal cyst followed by follicular cyst. Among the neoplastic tumours 78.70% were benign and 21.29% were malignant. Benign serous cysts were the commonest benign tumour followed by mature cystic teratoma and mucinous cyst. Serous cystadenocarcinoma was the commonest malignant tumour followed closely by endometrioid carcinoma and granulosa cell tumour. Krukenberg tumour, tumour metastatic to ovaries and non-Hodgkins lymphoma was also diagnosed during this period. Malignant germ cell tumours were seen in much younger age group followed by sex cord stromal tumours. Epithelial tumours were seen in much older age group. The morphologic diversity of ovarian masses poses many challenges. A specific diagnosis can usually be made by evaluating routinely stained slides but sometimes immunohistochemistry is required in difficult cases. Gross features also provide useful diagnostic clues

Role of needle aspiration biopsy in the diagnosis of mass in chest

Patients presenting at Mayo Hospital Chest Surgery Ward [Teaching Unit] who had mass lesion in the lung on X Ray were included in this study. Needle aspiration biopsy was done in all patients except for 05 cases. A total of 105 cases were studied between January 1997 to June 1999. Out of these, 80 were male, and 25 were female. There ages ranged between 10-90 years. Fine needle aspiration was also carried out in 101 out of 105 cases yielding an overall diagnostic value of 67.33°/a. It revealed tissue in 62 cases [61.39%], fluid in 28 cases [27.72%] Positive yield of needle aspiration biopsy in centrally located lesion was up to 23.53% whereas in peripherally located lesion mounted to 76.19%. This study revealed that needle aspiration biopsy of peripheral lung lesions or larger lesions is a very safe, quick and reliable method for establishing the diagnosis of mass chest. Moreover it showed better results in peripherally located lesions